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Educational Content

Single-Use Technologies: Millipore’s Vision for the Future

In the rapidly changing biomanufacturing industry, manufacturers require operational flexibility that saves time and money, while also providing quality and peace of mind. In this Educational webcast, Paul Chapman, Vice President of Downstream Processing for Millipore Corporation, discusses the innovation built into the Mobius FlexReady Solutions and how Millipore sees the future shaping-up for single-use technologies. More.

Downstream Case Study

During the process of moving to a new manufacturing facility, engineers at Genentech, Inc. performed small-scale studies to evaluate several candidates for a single-stage depth filter train to replace a traditional two-stage depth filtration train at the new facility. Click here to learn more about their methods and the results of their testing in this informative paper.

Single-Use, Continuous-Countercurrent, Multicolumn Chromatography

Due to recent improvements to bioprocess science, some monoclonal antibody titers have increased 30-fold over the past 15 years, causing significant challenges for downstream processes, in particular chromatographic capture. This article illustrates how multicolumn chromatography for bioprocessing (BioSMB) can provide an open, flexible and economical solution for the entire chromatography process. More.

Development of a High-Capacity MAb Capture Step

While Protein A affinity chromatography is traditionally used as the capture step for monoclonal antibodies, it can be expensive and cumbersome. This article discusses the methods and materials used to develop a high-capacity capture step using cation-exchange (CEX) chromatography replace the protein A step and meet the demands of increasing titers. More.