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 Perfusion! Jeopardy or the Ultimate Advantage?
In the past, perfusion has been viewed as a risky and undesirable manufacturing method to be avoided if at all possible. However, with the development of more sophisticated technology, this is no longer the case. In this webcast, Jason N. Carstens, PhD, of CMC Biologics, provides a high-level discussion of perfusion as an efficient method of manufacturing for biotherapeutics. More.
 Implementing Cost Reduction Strategies for HuMab Manufacturing Processes
In this informative paper, Dr. Arunakumari Alahari, Senior Director of Process Development at Medarex, Inc., discusses the various processes that can be implemented to reduce costs of manufacturing for the production of antibodies. Click here to learn more about how processes like perfusion and CHO production can help accelerate process development and reduce time-to-market.
Considering Cell Culture Automation in Upstream Bioprocess Development
Because cell culture automation for bioprocess development is an expensive investment, many factors should be carefully considered before a company commits to a purchase. In this paper, Tim Gryseels, a senior scientist at Pfizer, details the important steps in identifying and purchasing cell culture automation. More.
Monitoring ATP Status in the Metabolism of Production Cell Lines
When it comes to analyzing cell culture processes, established methods deliver useful but incomplete data. This paper discusses the process used to establish and evaluate an assay for rapid and reliable online measurement of intracellular ATP (adenoside-5′-triphosphate) to monitor the physiological state of cells in combination with other parameters (cell number, viability, and glucose consumption). More.
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A Single-Use, Scalable Perfusion Bioreactor System
BioProcess International, June 2009
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A Bioreactor System Based on a Novel Oxygen Transfer Method
BioProcess International, June 2008
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Determining the Effect of Raw Materials on Manufacturing-Scale Cell-Culture Performance
An Application of Mechanistic Mathematical Models
BioProcess International, June 2008
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A Review of Therapeutic Protein Expression By Mammalian Cells
BioProcess International, June 2008
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Analytical Technology and PAT
BioProcess International, January 2007
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Bioreactor Monitoring, Modeling, and Simulation
BioProcess International, January 2007
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Whole-Genome Evolution Technology
Improving Protein and Antibody Yields in Scalable Mammalian-Cell-Based Manufacturing
BioProcess International, May 2006
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